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enterprises to set up regional headquarters or research centres in   Recommendation 2    Establishing all-stage
            the Loop; moreover, the National Development and Reform       ancillary facilities to optimise biotech research
            Commission can launch a Shenzhen-Hong Kong Biotechnology      and development supply chain
            Collaborative Development Fund that pools together funds from
            the governments of the Guangdong Province, the Hong Kong SAR   Collaborative planning by the two governments is indispensable to
            and the Shenzhen Municipality. Along with the Hong Kong Growth   the development of biotech in the Loop. While Shenzhen has
            Portfolio previously established by the Government of the   established a Science and Technology Innovation Commission to
            Hong Kong Special Administrative Region (the Hong Kong SAR   coordinate planning and manage funding matters, the Hong Kong
            Government; or the Hong Kong government), part of the proposed   government has yet to put in place a designated body to advise on
            Fund shall be invested in promising biotech enterprises in the Loop   long-term scientific development and to promulgate a blueprint for
            to facilitate their development into unicorns in the medium term.  biotech development, which makes it difficult to discuss the
                                                                        planning of the Loop with Shenzhen. Drawing reference from
            We further recommend the joint establishment of a cross-border   economies like the US and Singapore, we recommend that the
            biotech mega research institute in the Loop by the University of   Hong Kong government set up a Science and Development Office
            Hong Kong, the Hong Kong University of Science and Technology   to provide forward-looking scientific advice on biotechnology,
            and the Chinese University of Hong Kong, together with Shenzhen   formulate a blueprint for the development of the biotech industry,
            institutions like the Shenzhen Institute of Advanced Technology,   optimise the government’s funding mechanism for research and
            the Chinese Academy of Sciences and the Southern University of   development (R&D) activities, formulate a funding allocation
            Science and Technology, with the cooperation of existing    strategy that aligns with the blueprint, and establish a peer review
            platforms and facilities in the GBA. The sharing of substantial   mechanism.
            funding and advanced facilities will foster interdisciplinary and
            cross-institutional collaboration. In the long-term, not only will this   The Loop also provides an opportune moment for optimising
            attract international talent, but also provide a comprehensive   ancillary facilities in support of the R&D process. For the preclinical
            career path for the local workforce, as well as further attract   research stage, the two governments should establish Good
            foreign enterprises by providing advanced research support to   Laboratory Practice (GLP) laboratories, in particular large-scale
            biotech enterprises. The institute will observe three principles:   animal laboratories. For phase 1 clinical trials, we suggest that the
            leverage cutting-edge research opportunities to better appeal to   approval process be expedited in Hong Kong to fully realise the
            world-class talent; resolve regional problems and increase the   city’s edge in clinical trials. Phases 2 and 3 trials are to be
            uniqueness of scientific research; and operate independently from   conducted with a multicentre approach. We recommend that
            universities to expedite the progress of advanced research.  HK-SZ cross-border multicentre clinical trials be coordinated in the
                                                                        Loop. Hong Kong’s internationalised clinical trial management and

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